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- A multi-pronged approach to targeting myeloproliferative neoplasms
- A new paradigm of machine learning-based structural variant detection
- A whole lot of junk or a treasure trove of discovery?
- Advanced imaging interrogation of pathogen induced NETosis
- Analysing the metabolic interactions in brain cancer
- Atopic dermatitis causes and treatments
- Boosting the efficacy of immunotherapy in lung cancer
- Building a cell history recorder using synthetic biology for longitudinal patient monitoring
- Characterisation of malaria parasite proteins exported into infected liver cells
- Deciphering the heterogeneity of the tissue microenvironment by multiplexed 3D imaging
- Defining the mechanisms of thymic involution and regeneration
- Delineating the molecular and cellular origins of liver cancer to identify therapeutic targets
- Developing computational methods for spatial transcriptomics data
- Developing drugs to block malaria transmission
- Developing models for prevention of hereditary ovarian cancer
- Developing statistical frameworks for analysing next generation sequencing data
- Development and mechanism of action of novel antimalarials
- Development of novel RNA sequencing protocols for gene expression analysis
- Discoveries in red blood cell production and function
- Discovering epigenetic silencing mechanisms in female stem cells
- Discovery and targeting of novel regulators of transcription
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Dissecting mechanisms of cytokine signalling
- Doublecortin-like kinases, drug targets in cancer and neurological disorders
- Epigenetic biomarkers of tuberculosis infection
- Epigenetics – genome wide multiplexed single-cell CUT&Tag assay development
- Exploiting cell death pathways in regulatory T cells for cancer immunotherapy
- Exploiting the cell death pathway to fight Schistosomiasis
- Finding treatments for chromatin disorders of intellectual disability
- Functional epigenomics in human B cells
- How do nutrition interventions and interruption of malaria infection influence development of immunity in sub-Saharan African children?
- Human lung protective immunity to tuberculosis
- Improving therapy in glioblastoma multiforme by activating complimentary programmed cell death pathways
- Innovating novel diagnostic tools for infectious disease control
- Integrative analysis of single cell RNAseq and ATAC-seq data
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigation of a novel cell death protein
- Malaria: going bananas for sex
- Mapping spatial variation in gene and transcript expression across tissues
- Mechanisms of Wnt secretion and transport
- Multi-modal computational investigation of single-cell communication in metastatic cancer
- Nanoparticle delivery of antibody mRNA into cells to treat liver diseases
- Naturally acquired immune response to malaria parasites
- Organoid-based discovery of new drug combinations for bowel cancer
- Organoid-based precision medicine approaches for oral cancer
- Removal of tissue contaminations from RNA-seq data
- Reversing antimalarial resistance in human malaria parasites
- Role of glycosylation in malaria parasite infection of liver cells, red blood cells and mosquitoes
- Screening for novel genetic causes of primary immunodeficiency
- Single-cell ATAC CRISPR screening – Illuminate chromatin accessibility changes in genome wide CRISPR screens
- Spatial single-cell CRISPR screening – All in one screen: Where? Who? What?
- Statistical analysis of single-cell multi-omics data
- Structural and functional analysis of epigenetic multi-protein complexes in genome regulation
- Structural basing for Wnt acylation
- Structure, dynamics and impact of extra-chromosomal DNA in cancer
- Targeted deletion of disease-causing T cells
- Targeting cell death pathways in tissue Tregs to treat inflammatory diseases
- The cellular and molecular calculation of life and death in lymphocyte regulation
- The role of hypoxia in cell death and inflammation
- The role of ribosylation in co-ordinating cell death and inflammation
- Understanding Plasmodium falciparum invasion of red blood cells
- Understanding cellular-cross talk within a tumour microenvironment
- Understanding the genetics of neutrophil maturation
- Understanding the roles of E3 ubiquitin ligases in health and disease
- Unveiling the heterogeneity of small cell lung cancer
- Using combination immunotherapy to tackle heterogeneous brain tumours
- Using intravital microscopy for immunotherapy against brain tumours
- Using nanobodies to understand malaria invasion and transmission
- Using structural biology to understand programmed cell death
- Validation and application of serological markers of previous exposure to malaria
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Professor Suzanne Cory

Director, 1996 – 2009
Professor Suzanne Cory is one of Australia’s most distinguished molecular biologists. As director of WEHI she energetically promoted science policy and research at both the national and international level.
Leadership
Under Professor Cory’s leadership, WEHI focused on four big global medical challenges: cancer, immunity, autoimmunity and infectious diseases.
New disciplines were embraced, including bioinformatics, structural biology, medicinal chemistry, genomics and large-scale targeted mutagenesis, enabling a truly multidisciplinary approach to tackling human disease.
Professor Cory, Dr Alan Harris, Professor Andreas Strasser
and Professor David Vaux
WEHI became a world leader in apoptosis research, following the discovery in 1988 by Professor David Vaux with Professor Cory and Professor Jerry Adams that the gene causing human follicular lymphoma acts by blocking the central cell death pathway.
Other key achievements of the period included:
- The identification, for the first time, of the breast stem cell
- The discovery of how immune responses are regulated by apoptosis, the natural program of cell death
- Pioneering a systems biology approach to understanding the immune system
- Development of vaccines for type 1 diabetes and coeliac disease
- A promising new treatment for rheumatoid arthritis
- Significant advances in malaria research including development of vaccine candidates
- Enormous strides forward in understanding the regulation of blood cell production
- Building development
Like her predecessor, Sir Gustav Nossal, Professor Cory was faced with an organisation rapidly outgrowing its premises.
She was instrumental in securing funding and key stakeholder support for the $185 million redevelopment of the Parkville building. Completed in 2012, the redeveloped building doubled the Institute’s research capacity and provided world-class laboratories to support and inspire our staff.
Clinical and commercial links
Rapidly translating new discoveries into improved treatments and preventative strategies for patients continued to be a core focus under Cory.
at the opening of the new Biotechnology Centre in 2002
The new Parkville building was designed to include a dedicated Clinical Translation Centre, strengthening links with clinicians in The Royal Melbourne Hospital and elsewhere.
WEHI also established the Biotechnology Centre within the research and development park at La Trobe University. The Bundoora campus provides facilities for drug discovery and development, to enhance our capacity for moving basic research discoveries further along the R&D pipeline.
Looking towards the next generation
Lynne Kosky at the Gene Technology Access Centre
To generate enthusiasm for science among school students, and to foster excellence in science education in schools, Cory initiated a partnership to establish the Gene Technology Access Centre (GTAC). GTAC provides innovative laboratory programs in cell and molecular biology for more than 6000 school students and 800 science teachers every year.
After her term as director finished, Professor Cory became President of the Australian Academy of Science. She continues her research at WEHI as an honorary distinguished research fellow in the Blood Cells and Blood Cancer division.