Cell Signalling and Cell Death

Cell Signalling and Cell Death

JAK2 bound to a blocking compound
The Cell Signalling and Cell Death division investigates the molecular mechanisms by which cells kill themselves, and the control processes that switch cell death on and off.
Many diseases are characterised by too much or too little cell death. Understanding how cell death processes are controlled will help us develop new treatments for cancers and immune disorders.

Health impact

Cancers: bowel cancer, breast cancer, lung cancer, leukaemia, lymphoma, myeloproliferative disorders, stomach cancer, blood cancers, ovarian cancer

Immune disorders: inflammatory bowel disease, psoriasis, rheumatoid arthritis, multiple sclerosis, Crohn's disease

Infectious diseases: vaccines

Division news

Division heads

Professor David Vaux

Professor John Silke

Lab heads

Associate Professor Grant Dewson

Associate Professor James Murphy

Division coordinator

Catherine McLean

Michelle Birrell, Administrative Officer