Associate Professor Scott Mueller - Doherty Institute for Infection and Immunity

Associate Professor Scott Mueller - Doherty Institute for Infection and Immunity

Davis Auditorium
Start Time: 
Mon, 05/08/2019 - 12:00pm
End Time: 
Mon, 05/08/2019 - 1:00pm

Dissecting the evolution of immune responses to infection

​Postgraduate lecture series hosted by Dr Greg Ebert

Associate Professor Scott Mueller is an NHMRC Senior Research Fellow and laboratory head in the Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity. Scott completed his PhD at The University of Melbourne with Prof Frank Carbone (2003), performed postdoctoral training in the USA at Emory University with Dr Rafi Ahmed and then at the National Institutes of Health (NIAID) with Dr Ronald Germain. He received an ARC QEII fellowship and started his laboratory in 2010.

Scott Mueller’s research is focused on dissecting the fundamental cellular processes involved in immune responses to infectious diseases in order to identify new targets for vaccine design and therapeutics. The priming of immune responses occurs within the organised microarchitecture of the secondary lymphoid organs, which is constructed by various subsets of stromal cells within which immune cells migrate, interact and become activated. He is interrogating cell dynamics and cell cell interactions in vivo from the perspective of the immune cells (lymphocytes, dendritic cells) and stromal cells to achieve a detailed understanding of these processes from the cell to the tissue level. Utilizing animal models and intravital microscopy techniques he has pioneered methods to image skin and revealed subsets of tissue-resident memory T cells that provide rapid, frontline defense against infections. Current research in his lab is also dissecting crosstalk between the immune system and the nervous system, identifying neuroimmune pathways influencing cell migration and immunity to infection and cancer.