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- A multi-pronged approach to targeting myeloproliferative neoplasms
- A new paradigm of machine learning-based structural variant detection
- A whole lot of junk or a treasure trove of discovery?
- Advanced imaging interrogation of pathogen induced NETosis
- Analysing the metabolic interactions in brain cancer
- Atopic dermatitis causes and treatments
- Boosting the efficacy of immunotherapy in lung cancer
- Building a cell history recorder using synthetic biology for longitudinal patient monitoring
- Characterisation of malaria parasite proteins exported into infected liver cells
- Deciphering the heterogeneity of the tissue microenvironment by multiplexed 3D imaging
- Defining the mechanisms of thymic involution and regeneration
- Delineating the molecular and cellular origins of liver cancer to identify therapeutic targets
- Developing computational methods for spatial transcriptomics data
- Developing drugs to block malaria transmission
- Developing models for prevention of hereditary ovarian cancer
- Developing statistical frameworks for analysing next generation sequencing data
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- Development of novel RNA sequencing protocols for gene expression analysis
- Discoveries in red blood cell production and function
- Discovering epigenetic silencing mechanisms in female stem cells
- Discovery and targeting of novel regulators of transcription
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Dissecting mechanisms of cytokine signalling
- Doublecortin-like kinases, drug targets in cancer and neurological disorders
- Epigenetic biomarkers of tuberculosis infection
- Epigenetics – genome wide multiplexed single-cell CUT&Tag assay development
- Exploiting cell death pathways in regulatory T cells for cancer immunotherapy
- Exploiting the cell death pathway to fight Schistosomiasis
- Finding treatments for chromatin disorders of intellectual disability
- Functional epigenomics in human B cells
- How do nutrition interventions and interruption of malaria infection influence development of immunity in sub-Saharan African children?
- Human lung protective immunity to tuberculosis
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- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigation of a novel cell death protein
- Malaria: going bananas for sex
- Mapping spatial variation in gene and transcript expression across tissues
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- Naturally acquired immune response to malaria parasites
- Organoid-based discovery of new drug combinations for bowel cancer
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- Removal of tissue contaminations from RNA-seq data
- Reversing antimalarial resistance in human malaria parasites
- Role of glycosylation in malaria parasite infection of liver cells, red blood cells and mosquitoes
- Screening for novel genetic causes of primary immunodeficiency
- Single-cell ATAC CRISPR screening – Illuminate chromatin accessibility changes in genome wide CRISPR screens
- Spatial single-cell CRISPR screening – All in one screen: Where? Who? What?
- Statistical analysis of single-cell multi-omics data
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- Using combination immunotherapy to tackle heterogeneous brain tumours
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- Using structural biology to understand programmed cell death
- Validation and application of serological markers of previous exposure to malaria
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Kaiseal Sarson-Lawrence

“A PhD shouldn’t be your whole life, just a part of it,” according to PhD student Mr Kaiseal Sarson-Lawrence.
As well as investigating how blood cell production is controlled, Kaiseal makes time for professional development, social activities and keeping fit.
From malaria to structural biology
Dr Nadia Kershaw.
Kaiseal first joined the Institute as an Honours student after undertaking a Bachelor of Science degree at the University of Melbourne.
“I was attracted by the Institute’s strong international reputation, and many of my lecturers had spoken in glowing terms about the Institute.
"I had looked at opportunities at several medical research institutes, and I found a project at the Institute studying malaria that interested me, which made up my mind about coming here,” he said.
Kaiseal enjoyed his Honours year, and chose to continue on to PhD studies. His PhD project, supervised by Associate Professor Jeff Babon and Dr Nadia Kershaw, investigates how blood cell development is controlled by cytokines (signalling proteins). “I’m looking at the structures of the membrane receptors that bind cytokines outside immature blood cells, transmitting signals into the cell and impacting how they develop.
“I’ve only recently started so at the moment I’m doing a lot of protein purifications and groundwork to ensure the proteins are behaving as we expect. In the future I will be using X-ray crystallography and cryo-electron microscopy (cryoEM) to study the structure of my proteins,” he said.
A supportive environment
Kaiseal said the Institute provides a very supportive environment for students.
“There is a large student cohort and regular social events and personal development opportunities to better prepare you for a career inside or outside of academia.
"You also get to work with and learn from people who are world leaders in their field and very passionate about what they do,” he said.
“The annual student retreat – run by the Institute’s student associate, WESA – is always a good time. It’s a full day of interesting guest speakers and then a bit of fun in the evening.”
Kaiseal has some advice for students: “it’s important to have things you enjoy doing outside of work to relief stress and take your mind off lab work when it’s not going so well. I’m very into health and fitness so if I’m not in the lab you can probably find me in the gym or out on the soccer field.”
After his PhD, Kaiseal is considering pursuing a career in academia, but first he’d like to take a holiday. “I took time off after Honours and it was probably the best life decision I’ve ever made!”