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- A multi-pronged approach to targeting myeloproliferative neoplasms
- A new paradigm of machine learning-based structural variant detection
- A whole lot of junk or a treasure trove of discovery?
- Advanced imaging interrogation of pathogen induced NETosis
- Analysing the metabolic interactions in brain cancer
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- Characterisation of malaria parasite proteins exported into infected liver cells
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- Defining the mechanisms of thymic involution and regeneration
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- Using combination immunotherapy to tackle heterogeneous brain tumours
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- Using structural biology to understand programmed cell death
- Validation and application of serological markers of previous exposure to malaria
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Professor Andrew Roberts
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Professor
Andrew
Roberts
MB BS Qld PhD Melbourne FRCPA FRACP
Laboratory Head; Joint Leader, Cancer Research and Treatments Theme
Division:
My research focuses on blood cancers – leukaemias, lymphomas and myeloma. My research aims to understand these diseases and to develop new treatments for them.
As well as leading a research laboratory, I jointly lead WEHI’s Cancer Research and Treatments theme. I am also a clinical haematologist at The Royal Melbourne Hospital and Peter MacCallum Cancer Centre.
Research interest
My lab collaborates closely with the clinical and laboratory researchers across the Victorian Comprehensive Cancer Centre, and with translational research colleagues at WEHI.
Major focuses of our research include:
- Molecular basis of leukemogenesis and lymphomagenesis
- Molecular basis of resistance to chemotherapy and targeted therapies
- BCL-2 inhibitors and BH3 mimetics
- Clinical trials of novel therapies
Professor Andrew Roberts and collaborators have shown that patients with an advanced form of leukaemia can achieve complete remission with a novel tablet treatment.
Starting with a landmark discovery in 1988, follow the story of how Institute research has driven development of a breakthrough anti-cancer drug.
The discovery and development of breakthrough anti-cancer drug venetoclax has seen four senior scientists from the Institute win the 2019 Prime Minister’s Prize for Innovation.
