Associate Professor Andrew Webb

Associate Professor Andrew Webb



Associate Professor Andrew Webb in the proteomics lab


Associate Professor

BSc (MSc) Monash PhD Monash

Laboratory Head

Our research applies the latest proteomics methods to understand how changes in proteins in our body influence health and disease.

In particular we are interested in developing new techniques to advance basic laboratory research and clinical studies. Ongoing research studies include:

  • Understanding the cell signalling pathways contributing to inflammatory conditions such as rheumatoid arthritis.
  • Developing a blood test to predict which children are at risk of developing rheumatic fever.
  • Detecting a test for detecting stomach cancer at early, more treatable stages.

Research interest 

We collaborate widely with scientists and clinicians to advanced proteomics technologies to identify and quantify proteins in cells and biofluids.

Our laboratory covers diverse range of areas that can be categorised into five key focus areas:

  • Interactions: Elucidation of protein-protein and protein-drug interactions
  • Protein dynamics: Investigating the mechanisms of protein function
  • Signalling: Investigation of signalling pathways (using phosphoproteomics and ubiquitin enrichment strategies)
  • Biomarkers: Identification of prognostic and diagnostic biomarkers of disease in biofluids
  • Epigenetics: Quantification of intact histones and their modifications in developmental and disease models
Dr Laura Dagley in a laboratory

Dr Laura Dagley is developing a blood test to improve how we detect acute rheumatic fever, a condition that is prevalent in Aboriginal communities and that can cause life-threatening heart disease.

We have discovered that cartilage plays an active role in the destruction and remodelling of joints seen in rheumatoid arthritis.

Side-by-side images of Cherie Chiang and Andrew Webb

WEHI’s Associate Professor Andrew Webb and the Royal Melbourne Hospital’s Associate Professor Cherie Chiang are developing an early diagnosis test for dementia at the Colonial Foundation Healthy Ageing Centre.