Selected publications

1. Nachbur U, Stafford C, Bankovacki A, Zhan Y, Lindqvist L, Fiil B, Khakam Y, Ko HJ, Sandow J, Falk H, Holien J, Chau D, Hildebrand J, Vince J, Sharp P, Webb AI, Jackman K, Mühlen S, Kennedy C, Lowes K, Murphy J, Hansen MG, Parker M, Hartland E, Lew A, Huang D, Lessene G, and Silke J. A novel RIPK2 inhibitor delays NOD signalling complex formation yet prevents inflammatory cytokine production. Nature Communications. Accepted Jan 2015.
2. Hildebrand JM, Tanzer MC, Lucet IS, Young SN, Spall SK, Sharma P, Pierotti C, Garnier JM, Dobson RC, Webb AI, Tripaydonis A, Babon JJ, Mulcair MD, Scanlon MJ, Alexander WS, Wilks AF, Czabotar PE, Lessene G, Murphy JM, Silke J. Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Proceedings of the National Academy of Sciences. 111,42,15072-15077, 2014. PMID: 25288762
3. Wong W*, Webb AI*, Olshina MA, Infusini G, Tan YH, Hanssen E, Catimel B, Suarez C, Condron M, Angrisano F, Nebi T, Kovar DR, Baum J. A Mechanism for Actin Filament Severing by Malaria Parasite Actin Depolymerizing Factor 1 via a Low Affinity Binding Interface. Journal of Biological Chemistry. 289,7,4043-4054, 2014. PMID: 24371134
4. Chambers JM, Lindqvist LM, Webb AI, Huang DC, Savage GP, Rizzacasa MA. Synthesis of biotinylated Episilvestrol: highly selective targeting of the translation factors eIF4AI/II. Organic letters. 15,6,1406-1409, 2013. PMID: 23461621
5. Etemadi N, Webb AI, Bankovacki A, Silke J, Nachbur U. Progranulin does not inhibit TNF and lymphotoxin-α signalling through TNF receptor 1. Immunology and cell biology. 91(10) 661-4, 2013. PMID: 24100384
6. Pearson JS, Giogha C, Ong SY, Kennedy CL, Kelly M, Robinson KS, Lung TW, Mansell A, Riedmaier P, Oates CV, Zaid A, Mühlen S, Crepin VF, Marches O, Ang CS, Williamson NA, O'Reilly LA, Bankovacki A, Nachbur U, Infusini G, Webb AI, Silke J, Strasser A, Frankel G, Hartland EL. A type III effector antagonizes death receptor signalling during bacterial gut infection, Nature, 501,7466,247-251, 2013. PMID: 24025841
7. Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS., The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism, Immunity, 39,3,443-453, 2013. PMID: 24012422
8. Dejnirattisai W*, Webb AI*, Chan V, Jumnainsong A, Davidson A, Mongkolsapaya J, Screaton G. Lectin switching during dengue virus infection. Journal of Infectious Diseases. 203,12,1775-1783, 2011. PMID: 21606536
9. Gerlach B*, Cordier SM*, Schmukle AC*, Emmerich CH*, Rieser E*, Haas TL*, Webb AI*, Rickard JA, Anderton H, Wong WW, Nachbur U, Gangoda L, Warnken U, Purcell AW, Silke J, Walczak H. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature. 471,7340,591-596, 2011. PMID: 21455173
10. Theodossis A1, Guillonneau C, Welland A, Ely LK, Clements CS, Williamson NA, Webb AI, Wilce JA, Mulder RJ, Dunstone MA, Doherty PC, McCluskey J, Purcell AW, Turner SJ, Rossjohn J. Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition. Proceedings of the National Academy of Sciences. 107,12,5534-5539, 2010. PMID: 20212169

*co-first authored