I am a medical oncologist who is heavily involved in drug development. I aim to develop better treatments for cancer through laboratory research and clinical trials.

My research focuses on matching people with the best treatment for their individual cancer. In particular, I am studying how the genome of cancer cells interacts with the body’s anti-tumour immune response.

Ultimately my research could lead to better ways of personalising treatment for cancer patients.

Research interest

My research is focused on assessing potential new anti-cancer drugs through early phase clinical trials, mostly in urological cancers.

Some of these drugs are molecularly targeted and require molecular pre-selection of appropriate trial participants through molecular profiling using next generation sequencing. 

Other new drugs involve targeting and activating the immune system within individual patients, to generate an anti-cancer effect. 

My laboratory-based research is also focused on urological cancers, particularly testicular and bladder cancer. 

I am currently working with a multinational team to determine why some testicular cancers do not respond well to chemotherapy.

In bladder cancer, I am working to determine why some patients do not benefit from immunotherapy. This involves the generation and analysis of real world data, together with the use of molecular profiling and gene expression studies to help determine how to get the right drug to the right patient at the right time.