Selected publications

1. Policheni AN, Teh CE, Robbins AK, Tuzlak S, Strasser A, Gray DHD. PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease. Proc Natl Aced Sci U S A Apr 12;119(15):e2120149119. doi: 10.1073/pnas.212019119. Epub 2022 Apr 8. PMID: 35394861
2. Teh CE*, Preston SP*, Robbins AK, Stutz MD, Cooney J, Clark MP, Policheni AN, Allison CC, Mackiewicz L, Arandjelovic P, Ebert G, Doerflinger M, Tan T, Rankin LC, Teh PP, Belz GT, Kallies A, Strasser A, Pellegrini M*, Gray DHD* (* equal contribution). Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage. Sci Immunol. 2022 Mar 25;7(69):eabn8041. doi: 10.1126/sciimmunol.abn8041. Epub 2022 Mar 25 PMID: 35333545
3. Melanie Heinlein, Luke C Gandolfo, Kelin Zhao, Charis E Teh, Nghi Nguyen, Jonathan B Baell, Yael Goldfarb, Jakub Abramson, Johannes Wichmann , Anne K Voss, Andreas Strasser, Gordon K Smyth, Tim Thomas, Daniel H D Gray. The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance. Sci Immunol. 2022 Jan 21;7(67):eabb6032. doi: 10.1126/sciimmunol.abb6032. Epub 2022 Jan 21. PMID: 35061506
4. Jain R., Zhao K., Sheridan J.M., Heinlein M., Kupresanin F., Abeysekera W., Hall C., Rickard J., Bouillet P., Walczak H., Strasser A., Silke J. and Gray D.H.D. Dual roles for LUBAC signaling in thymic epithelial cell development and survival. Cell Death and Differentiation, Aug 11 doi 10.1038/s41418-021-00850-8.
5. Teh, C.E.*, Robbins, A.K.*, Henstridge, D.C., Dewson, G., Diepstraten, S.T., Kelly, G., Febbraio, M.A., Gabriel, S.S., O'Reilly, L.A., Strasser, A., and Gray, D.H.D. (* co-first authors) MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells. Cell Death and Differentiation. 2020 Jul 1. doi: 10.1038/s41418-020-0585-1.
6. Teh, C.E., Gong, J.N., Segal, D., Tan, T., Vandenberg, C.J., Fedele, P.L., Low, M.S.Y., Grigoriadis, G., Harrison, S.J., Strasser, A., Roberts, A.W., Huang, D.C.S., Nolan, G.P.*,#, Gray, D.H.D.*,#, and Ko, M.E*. Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells. (* co-senior author; # corresponding authors) Cell Death and Differentiation. 2020 Jul;27(7):2217-2233. doi: 10.1038/s41418-020-0498-z.
7. Jain, R., Sheridan, J.M., Policheni, A., Heinlein, M., Gandolfo, L.C., Dewson, G., Smyth, G.K., Sansom, S.N., Fu, N.Y., Visvader, J.E., Hollander, G.A., Strasser, A., and Gray, D.H.D.  A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood 2017, Dec 7;130(23):2504-2515. Doi: 10.1182/blood-2017-03-771576. 
8. Teh, C.E., Lalaoui, N., Jain, R., Policheni, A.N., Heinlein, M., Alvarez-Diaz, S., Sheridan, J.M., Rieser, E., Deuser, S., Darding, M., Koay, H.-F., Hu, Y., Kupresanin, F., O'Reilly, L.A., Godfrey, D.I., Smyth, G.K., Bouillet, P., Strasser, A., Walczak, H., Silke, J., and Gray, D.H.D. Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis. Nature Communications 2016; 7: 13353. Doi: 10.1038/ncomms13353.
9. Liston, A., and Gray, D.H.D. Homeostatic control of regulatory T cell diversity. Nature Reviews Immunology 2014; 14(3): 154-65. ISI Web of Science Highly Cited Paper
10. Pierson, W., Cauwe, B., Policheni, A., Schlenner, S.M., Franckaert, D., Berges, J., Humblet-Baron, S., Schonefeldt, S., Herold, M.J., Hildeman, D., Strasser, A., Bouillet, P., Lu, L.-F., Matthys, P., Freitas, A.A., Luther, R.J., Weaver, C.T., Dooley, J., Gray, D.H.D.*, and Liston, A.* (joint senior/corresponding authors) Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3(+) regulatory T cells. Nature Immunology 2013; 14(9): 959-65.

Further publications