Selected publications

1. Teh CE, Lalaoui N, Jain R, Policheni AN, Heinlein M, Alvarez-Diaz S, Sheridan JM, Rieser E, Deuser S, Darding M, Koay HF, Hu Y, Kupresanin F, O'Reilly LA, Godfrey DI, Smyth GK, Bouillet P, Strasser A, Walczak H, Silke J, Gray DH. Linear ubiquitin chain assembly complex coordinates late thymic T cell differentiation and regulatory T cell homeostasis Nat. Comm. 2016 Nov 18;7:13353. doi: 10.1038/ncomms13353 PMID: 27857075
2. Wong K, Lister NL, Barsanti M, Lim JM, Hammett MV, Khong DM, Siatskas C, Gray DH, Boyd RL, Chidgey AP. Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus. Cell Reports Aug 21;8(4):1198-209. PMID: 25131206
3. Liston A, Gray DH. Homeostatic control of regulatory T cell diversity. Nat. Rev. Immunol. 2014 Mar;14(3):154-65. PMID: 24481337
4. Pierson W, Cauwe B, Policheni A, Schlenner SM, Franckaert D, Berges J, Humblet-Baron S, Schönefeldt S, Herold MJ, Hildeman D, Strasser A, Bouillet P, Lu LF, Matthys P, Freitas AA, Luther RJ, Weaver CT, Dooley J, Gray DH, Liston A. Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells. Nat. Immunol. 2013 Sep;14(9):959-65. PMID: 23852275
5. Danso-Abeam D, Staats KA, Franckaert D, Van Den Bosch L, Liston A, Gray DH, Dooley J. Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism. Eur J Immunol. 2013 Jan;43(1):75-84. PMID: 23041971
6. Gray DH, Kupresanin F, Berzins SP, Herold MJ, O'Reilly LA, Bouillet P, Strasser A. The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance to organ-specific antigens. Immunity. 2012 Sep 21;37(3):451-62. PMID: 22960223
7. Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. XIAP discriminates between type I and type II FAS-induced apoptotis. Nature. 2009 Aug 20;460(7258):1035-9. PMID: 19626005
8. Seach N, Ueno T, Fletcher AL, Lowen T, Mattesich M, Engwerda CR, Scott HS, Ware CF, Chidgey AP, Gray DH, Boyd RL. The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells. J Immunol. 2008 Apr 15;180(8):5384-92. PMID: 18390720
9. Gray DH, Gavanescu I, Benoist C, Mathis D. Danger-free autoimmunity in Aire-deficient mice. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18193-8. PMID: 17991771
10. Gray D, Abramson J, Benoist C, Mathis D. Proliferative arrest and rapid turnover of thymic epithlial cells expressing Aire. J Exp Med. 2007 Oct 29;204(11):2521-8. PMID: 17908938