Selected publications

1. Jain R, Sheridan JM, Policheni A, Heinlein M, Gandolfo LC, Dewson G, Smyth GK, Sansom SN, Fu NY, Visvader JE, Hollander GA, Strasser A, Gray DHD. A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood. 2017, Dec 7;130(23):2504-2515. PMID: 28972012
2. Sheridan J, Keown A, Policheni A, Roesley SNA, Rivlin N, Kadouri N, Ritchie ME, Jain R, Abramson J, Heng TSP, Gray DHD. Thymospheres are formed by mesenchymal cells with the potential to form adipocytes but not epithelial cells. Cell Reports. 2017, Oct 24;21(4):934-942. PMID: 29069601
3. Nolan E, Savas P, Policheni AN, Darcy PK, Vaillant F, Mintoff CP, Dushyanthen S, Mansour M, Pang JB, Fox SB, Kathleen Cuningham Foundation Consortium for Research into Familial Breast C, Perou CM, Visvader JE, Gray DHD*, Loi S*, Lindeman GJ*. (*co-senior authors) Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer. Sci Transl Med 2017; 9(393). PMID: 28592566
4. Daley SR, Teh C, Hu DY, Strasser A, Gray DHD. Cell death and thymic tolerance. Immunol Rev. 2017; 277(1): 9-20. PMID: 28462532
5. Teh CE, Lalaoui N, Jain R, Policheni AN, Heinlein M, Alvarez-Diaz S, Sheridan JM, Rieser E, Deuser S, Darding M, Koay HF, Hu Y, Kupresanin F, O'Reilly LA, Godfrey DI, Smyth GK, Bouillet P, Strasser A, Walczak H, Silke J, Gray DH. Linear ubiquitin chain assembly complex coordinates late thymic T cell differentiation and regulatory T cell homeostasis Nat. Comm. 2016 Nov 18;7:13353. doi: 10.1038/ncomms13353 PMID: 27857075
6. Wong K, Lister NL, Barsanti M, Lim JM, Hammett MV, Khong DM, Siatskas C, Gray DH, Boyd RL, Chidgey AP. Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus. Cell Reports Aug 21;8(4):1198-209. PMID: 25131206
7. Liston A, Gray DH. Homeostatic control of regulatory T cell diversity. Nat. Rev. Immunol. 2014 Mar;14(3):154-65. PMID: 24481337
8. Pierson W, Cauwe B, Policheni A, Schlenner SM, Franckaert D, Berges J, Humblet-Baron S, Schönefeldt S, Herold MJ, Hildeman D, Strasser A, Bouillet P, Lu LF, Matthys P, Freitas AA, Luther RJ, Weaver CT, Dooley J, Gray DH, Liston A. Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells. Nat. Immunol. 2013 Sep;14(9):959-65. PMID: 23852275
9. Danso-Abeam D, Staats KA, Franckaert D, Van Den Bosch L, Liston A, Gray DH, Dooley J. Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism. Eur J Immunol. 2013 Jan;43(1):75-84. PMID: 23041971
10. Gray DH, Kupresanin F, Berzins SP, Herold MJ, O'Reilly LA, Bouillet P, Strasser A. The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance to organ-specific antigens. Immunity. 2012 Sep 21;37(3):451-62. PMID: 22960223