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- Novel checkpoints NK cells emerge as key players in IO
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- Associate Professor Marco Herold Marco Herold
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- Education
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- 3D and 4D imaging of thymic T cell differentiation
- Activating https://www.wehi.edu.au/node/add/individual-student-research-page#Parkin to treat Parkinson’s disease
- Activation, regulation, and biological roles of E3 ubiquitin ligases
- Bioinformatics methods for detecting and making sense of somatic genomic rearrangements
- Characterising regulatory T cells in coeliac disease
- Computational melanoma genomics
- Deep profiling of blood cancers during targeted therapy
- Defining the role of necroptosis in platelet production and function
- Determining the migration signals leading to protective immune responses
- Developing mucolytics to treat chronic respiratory diseases
- Developing new tools to visualise necroptotic cell death
- Development of live-cell, automated microscopy techniques for studying malaria
- Development of tools to inform malaria vaccine design
- Discovering new genetic causes of primary antibody deficiencies
- Discovery of novel drug combinations for the treatment of bowel cancer
- Dissecting the induction and integration of T cell migration cues
- Drug targets and compounds that block growth of malaria parasites
- Effects of nutrition on immunity and infection in Asia and Africa
- Eosinophil and neutrophil heterogeneity
- Eosinophil maturation
- Epigenetic regulation of systemic iron homeostasis
- Functional differences between young and old platelets
- Generation of cytokine antagonists
- Genetic dissection of mechanisms of Plasmodium invasion
- Genomic characterisation of epigenetic regulators involved in X inactivation
- High resolution 3-dimensional imaging to characterise metastatic cancers
- High-resolution imaging of host cell invasion by the malaria parasite
- Home renovations: understanding how Toxoplasma redecorates its host cell
- How the epigenetic regulator SMCHD1 works and how to target it to treat disease
- Human monoclonal antibodies against malaria infection
- Identification of malaria parasite entry receptors
- Identification of new therapeutic opportunities for pancreatic cancer
- Identifying disease-causing haplotypes with hidden Markov models
- Interleukin-11 in gastrointestinal bacterial infections
- Investigating mechanisms of cell death and survival using zebrafish
- Investigating new paths to selective modulation of potassium channels
- Let me in! How Toxoplasma invades human cells
- Long-read sequencing for transcriptome and epigenome analysis
- Macro-evolution in cancer
- Mapping DNA repair networks in cancer
- Mapping how multiple malaria episodes are related
- Modelling gene regulatory systems
- Modulation of immune responses by immunosuppressive chemokines
- Molecular basis for inherited Parkinson’s disease mechanism of PINK1
- Mucus at the molecular level
- Novel cell death and inflammatory modulators in lupus
- Plasmodium vivax host-parasite interactions: impact on immunity
- Predicting drug response in cancer
- Programming T cells to defend against infections
- Reconstructing the immune response: from molecules to cells to systems
- Regulation of cytokine signalling
- Screening for regulators of jumping genes
- Target identification of potent antimalarial agents
- Targeting the immune system in cancer
- The role of interleukin-11 in acute myeloid leukaemia
- Transmembrane control of type I cytokine receptor activation
- Uncovering the roles of long non-coding RNAs in human bowel cancer
- Understanding retinal eye diseases with retinal transcriptomic data analysis
- Understanding the role of stromal cells in pancreatic cancer growth
- Unravelling the tumour suppressor network in models of lung cancer
- Utilising pre-clinical models to discover novel therapies for tuberculosis
- Zombieland: evolution of a dead enzyme that kills cells by necroptosis
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Justin Boddey-Resources
Researcher:
Resources
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$4.6M boost in search for new malaria drugs - Institute news story, 1 May 2018
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Plasmepsins on the antimalarial hit list. Justin A. Boddey. Science 27 Oct 2017: Vol. 358, Issue 6362
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Australian researchers make malaria breakthrough - ABC Radio
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Carbohydrates may be the key to a better malaria vaccine - Institute news story, 15 September 2017
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Malaria parasites ‘walk through walls’ to infect humans - Institute news story, 30 March 2017
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Crucial malaria discovery validated by international researchers - Institute news story, 3 February 2016
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Nature Index 2016 Australia and New Zealand - Cover image
Videos
Super Content:
Nature Index ranks the Institute as the top medical research institute in Australia
Visualisation of the parasite infection inside a pregnant female mosquito.
