Selected publications

1. Best SA*, Hess JB*, Souza-Fonseca-Guimaraes F, Cursons J, Kersbergen A, Dong X, Rautela J, Hyslop SR, Ritchie ME, Davis MJ, Leong TL, Irving TL, Steinfort D, Huntington ND & Sutherland KD. (2020). Harnessing Nature Killer Immunity in Metastatic SCLC. J Thorac Oncol. 15(9):1507-1521 PMID: 32470639
2. Burr ML, Sparbier CE, Chan, KL, Chan Y, Kersbergen A, Lam EYN, Azidis-Yates E, Vassiliadis D, Bell CC, Gilan O, Jackson S, Tan L, Wong S, Hollizek S, Michalak EM, Siddle H, McCabe MT, Prinjha RK, Solomon BJ, Sandhu S, Dawson SJ, Beavis PA, Tothill R, Cullinane C, Lehner PJ, Sutherland KD and Dawson MA. (2018). An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer. Cancer Cell. 2019 Sep 24. PMID: 31564637
3. Best SA, Ding S, Kersbergen A, Dong X, Song JY, Xie Y, Reljic B, Li K, Vince JE, Rathi V, Wright GM, Ritchie ME and Sutherland KD. (2019). Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma. Nat Commun. 2019 Sep 13;10(1):4190. PMID: 31519898
4. Best SA*, Harapas C*, Kersbergen A, Rathi V, Asselin-Labat ML and Sutherland KD. (2018). FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium. Oncogene 37(46):6096-6104. *Joint-first authors. PMID: 29991799
5. Best SA, De Souza DP, Kersbergen A, Policheni AN, Dayalan S, Tull D, Rathi V, Gray DH, Ritchie ME, McConville MJ and Sutherland KD. (2018). Synergy between the KEAP1/NRF2 and PI3K pathway drives non-small cell lung cancer with an altered immune microenvironment. Cell Metab. 2018 Apr 3;27(4):935-943.e4. PMID: 29526543
6. Ferone G, Song JY, Sutherland KD, Bhaskaran R, Monkhorst K, Lambooij JP, Proost N, Gargiulo G and Berns A. (2016). SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin. Cancer Cell 30(4):519-532. PMID: 27728803
7. Sutherland KD, Song J-Y, Kwon MC, Proost N, Zevenhoven J, Berns A. Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4952-7. PMID: 24586047
8. Sutherland K, Proost N, Brouns I, Adriaensen D, Song JY, Berns A. Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell. 2011;19(6):754-64. PMID: 21665149
9. Sutherland KD and Berns A. Cell of origin of lung cancer. Molecular Oncology. 2010;4(5):397-403. PMID: 20594926

​Further publications