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- A new regulator of stemness to create dendritic cell factories for immunotherapy
- Advanced methods for genomic rearrangement detection
- Control of cytokine signaling by SOCS1
- Defining the protein modifications associated with respiratory disease
- Delineating the pathways driving cancer development and therapy resistance
- Developing a new drug that targets plasmacytoid dendritic cells for the treatment of lupus
- Development and mechanism of action of novel antimalarials
- Development of a novel particle-based malaria vaccine
- Development of tau-specific therapeutic and diagnostic antibodies
- Discovering novel therapies for major human pathogens
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Epigenetic biomarkers of tuberculosis infection
- Essential role of glycobiology in malaria parasites
- Evolution of haematopoiesis in vertebrates
- Human lung protective immunity to tuberculosis
- Identifying novel treatment options for ovarian carcinosarcoma
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigating the role of mutant p53 in cancer
- Microbiome strain-level analysis using long read sequencing
- Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy
- Modelling spatial and demographic heterogeneity of malaria transmission risk
- Naturally acquired immune response to malaria parasites
- Predicting the effect of non-coding structural variants in cancer
- Structural basis of catenin-independent Wnt signalling
- Structure and biology of proteins essential for Toxoplasma parasite invasion
- T lymphocytes: how memories are made
- TICKER: A cell history recorder for longitudinal patient monitoring
- Targeting host pathways to develop new broad-spectrum antiviral drugs
- Targeting post-translational modifications to disrupting the function of secreted proteins
- Targeting the epigenome to rewire pro-allergic T cells
- Targeting the immune microenvironment to treat KRAS-mutant adenocarcinoma
- The E3 ubiquitin ligase Parkin and mitophagy in Parkinson’s disease
- The molecular controls on dendritic cell development
- Understanding malaria infection dynamics
- Understanding the genetics of neutrophil maturation
- Understanding the neuroimmune regulation of innate immunity
- Understanding the proteins that regulate programmed cell death at the molecular level
- Using cutting-edge single cell tools to understand the origins of cancer
- When healthy cells turn bad: how immune responses can transition to lymphoma
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Melissa Davis - Publications
Researcher:
Selected publications
- Detchokul S, Elangovan A, Crampin EJ, Davis MJ* and Frauman AG* (*Co-senior authors). Network analysis of an in vitro model of androgen-resistance in prostate cancer. BMC Cancer. 2015 Nov 10; 15:883. PMID: 26553226
- Cursors J, Leuchowius KJ, Waltham M, Thomaskovic-Crook E, Foroutan M, Bracken CP, Redfern A, Crampin EJ, Street I*, Davis MJ*, and Thompson EW* (*Co-senior authors). Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines. Cell Com. Sig. 2015 May 15; 13:26. PMID: 25975820
- Budden DM, Hurley DG, Cursors J, Markham JF, Davis MJ and Crampin EJ. Predicting expression: the complementary power of histone modification and transcription factor binding data. Epigenetics Chromatin. 2014 Nov 24; 7(1):36. PMID: 25489339
- Genovese LA, Ng CG, Davis MJ, Remke M, Taylor MD, Adams DJ, Rust AG, Ward JM, Ban KH, Jenkins NA, Copeland NG, Wainwright BJ. Sleeping Beauty mutagenesis in a mouse medulloblastoma model identifies networks that discriminate between human molecular subgroups. PNAS. 2013 Nov 12; 110(46):E4325-34. PMID: 24167280
- Davis MJ and Ragan MA. Understanding cellular function and disease with comparative pathway analysis. Genome Med. 2013 Jul 26; 5(7):64. PMID: 23889971
- Collins BM, Davis MJ, Hancock JF and Parton RG. Structure-based reassessment of the cave-in signalling model: do caveolae regulate signalling through caveolin-protein interactions? Dev Cell. 2012 Jul 17; 23(1):11-20. PMID: 22814599
- Davis MJ, Shin CJ, Jing N and Ragan MA. Rewiring the dynamic interactome. Mol Biosyst. 2012 Aug; 8(8):2054-66. PMID: 22729145
- Davis KM, Hanson KA, Clark F, Zhang F, Kasukawa T, Kai C, Kawai J, Carninci P and Teasdale RD. Differential use of signal peptides and membrane domains is a common occurrence in the protein output of transcriptional units. PLoS Genetics. 2006 Apr; 2(4):e46. PMID: 16683029
- Carninci P, (Davis MJ, 18th of 195 authors) and Hayashizaki Y. The Transcriptional landscape of the mammalian genome. Science. Sep2; 309(5740):1559-63. PMID: 16141072
- Kanapin A, Batalov S, Davis MJ, Gough J, Grimmond S, Kawaji H, Margrane M, Matsuda H, Schonbach C, Teasdale RD, RIKEN GER Group and Yuan Z. Mouse Proteome Analysis. Genome Res. 2003 Jun; 13(6B):1335-44. PMID: 12819131
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